Common symptoms of Epson ink cartridge issues include inconsistent or streaky printing, faded or missing colors, error messages indicating low ink levels or cartridge recognition errors, and ink smudges on printed documents. Additionally, the printer may produce blank pages or exhibit poor print quality despite recently replacing the ink cartridges. If you encounter any of these symptoms, it's advisable to inspect the ink cartridges for any visible damage or leaks, ensure they are installed correctly, and perform a printhead cleaning or alignment if necessary to troubleshoot and resolve the issue.